Today I was told by the MLC Cad applications tech I was working with that CNC Software is now aware of the issue and will be addressing it within the next update.

You rock man. I've been hitting alt+t this whole time to no avail only to find out that clicking the graphics window before hand is the fix. This is definitely unique to 2022 but I'm glad there's a quick and easy work around. Appreciate the help!

I'm experiencing the same issue. It's driving me nuts. I reached out to our Cam Reseller - MLC Cad and worked with there tech over the phone. We tried a slew of things, reinstalling Mastercam, scrubbing my configurations and started with the default settings, changing the directory of the MyMasterCam Folder and a lot of other things that didn't seem relevant to me but nothing stuck. He then reached out to CNC Software and they said they haven't heard of this problem and chalked it up as a "malware, virus, ransomware or corrupt windows o/s problem". I'm frustrated because I don't think that's the issue. Hopefully they'll address it on the next update. Until then I'm just going back into my cofiguration settings and turning "display toolpath" back on every time it turns its self off, no need to close and restart Mastercam